Fmoc-β-Ala-D-Ala-OH AAD Impurity Reseach Building Block

High-purity Fmoc-β-Ala-D-Ala-OH for Impurity Research and pharmaceutical development.

The primary application is in Solid-Phase Peptide Synthesis.

Functions:

• Used as a pre-assembled dipeptide fragment (β-Ala-D-Ala)

• Fmoc group protects the N-terminus during peptide chain elongation

• C-terminal –COOH allows further coupling to other amino acids

Advantages:

• reduces the number of coupling steps

• improves synthesis efficiency and overall yield

• useful in synthesizing longer peptide sequences

This fragment can be incorporated into bioactive peptides or therapeutic peptides.

Roles in drug development:

• D-Alanine increases resistance to enzymatic degradation

• improves metabolic stability of peptide molecules

• helps modify peptide conformation

The β-alanine residue acts as a flexible spacer in peptide chains.

Functions:

• increases flexibility in peptide backbone

• adjusts the distance between functional residues

• reduces steric hindrance in peptide–receptor interactions

This building block is also used in:

• research peptides

• peptide analog development

• peptide probes or conjugates

Small packages (1g, 25g, 1Kg, 25Kg) can be shipped by Express (DHL, FedEx, EMS, etc.). Large packages (100kg and more than 100Kg) can be transported by Air or Sea. All transportation is arranged according to customer requirements.